2-Amino-5-<wbr/>fluorobenzoic Acid

2-Amino-5-fluorobenzoic Acid

CAT N°: 16669
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From 74.00 62.90

2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae.{27254} Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the TRP1 marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasmid manipulations.{27254}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-amino-5-fluoro-benzoic acid
  • Correlated keywords
    • microbiology counterselection antimetabolite tryptophan pathway TRP1 genetic marker yeast S. cerevisiae Saccharomyces positive selection plasmid vector biochemical 675575-38-9 NSC513308 toxic anti-metabolite strain anthranilic acid feedback inhibition resistant 1891087-22-1
  • Product Overview:
    2-Amino-5-fluorobenzoic acid is a toxic antimetabolite for the tryptophan pathway in yeast that can be used to counterselect for TRP1, a commonly used genetic marker in S. cerevisiae.{27254} Because this trp1 strain lacks the enzymes required for the conversion of anthranilic acid to tryptophan, it is resistant to 2-amino-5-fluorobenzoic acid feedback inhibition, enabling a growth-based, positive selection of the TRP1 marker. 2-Amino-5-fluorobenzoic acid is frequently used in genetic procedures that involve plasmid manipulations.{27254}

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