(1R,9S)-(–)-<wbr/>?-Hydrastine

(1R,9S)-(–)-?-Hydrastine

CAT N°: 22363
Price:

102.00 86.70

(1R,9S)-(–)-?-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 µM in PC12 cells) by inhibiting tyrosine hydroxylase activity.{38222,38223} It inhibits dopamine release with an IC50 value of 66.5 µM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.{38224,38225}

We also advise you