TAF 10 Peptide
TAF 10 Peptide
TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity.{16903} One vial of this peptide...
€191.00
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From €231.00 €196.35
From €231.00 €196.35
17(R)-Resolvin D3 (17(R)-RvD3) is an aspirin-triggered epimer of resolvin D3 (Item No. 13834).{25262} It is produced from docosahexaenoic acid (DHA; Item No. 90310) by COX-2 in the presence of aspirin via a 17(R)-hydroperoxy DHA (17(R)-HDHA; Item No. 10005099) intermediate and has been found in mouse inflammatory exudates.{25262,45355} 17(R)-RvD3 reduces transmigration of isolated human polymorphonuclear cells (PMNs) and induces efferocytosis of apoptotic PMNs by macrophages.{45355} 17(R)-RvD3 (10 ng/animal) reduces transmigration of neutrophils into the peritoneal cavity, as well as decreases the levels of IL-6 and increases the levels of IL-10 in inflammatory exudate in a mouse model of zymosan-induced peritonitis. It activates GPR32 in a ?-arrestin reporter assay and increases phagocytosis to a greater degree in CHO cells overexpressing GPR32 compared to mock-transfected cells. 17(R)-RvD3 increases phagocytosis of etoposide-generated tumor cell debris by monocyte-derived macrophages in H460 human lung carcinoma cells in a concentration-dependent manner.{45356} It also inhibits tumor growth in a mouse model of Lewis lung carcinoma when administered at a dose of 0.6 µg/kg per day.
Territorial Availability: Available through Bertin Technologies only in France
| Size | 10 µg, 100 µg, 25 µg, 50 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 1427475-53-3 |
| Molecular formula | C22H32O5 |
| Smiles | O[C@H](C/C=CCC)/C=C/C=CC[C@@H](O)/C=C/C=C/C=C[C@@H](O)CCC(O)=O, O[C@H](C/C=CCC)/C=C/C=CC[C@@H](O)/C=C/C=C/C=C[C@@H](O)CCC(O)=O, O[C@H](C/C=CCC)/C=C/C=CC[C@@H](O)/C=C/C=C/C=C[C@@H](O)CCC(O)=O, O[C@H](C/C=CCC)/C=C/C=CC[C@@H](O)/C=C/C=C/C=C[C@@H](O)CCC(O)=O |
| Molecular weight | 376,5 |
| Custom code | 2916.19 |
| Formulation | A solution in ethanol |
| Purity | ≥90% |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
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