17-<wbr/>trifluoromethylphenyl trinor Prostaglandin F<sub>2?</sub> isopropyl ester

17-trifluoromethylphenyl trinor Prostaglandin F2? isopropyl ester

CAT N°: 10010062
Price:

From 85.00 72.25

Prostaglandin F2? (PGF2?), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 17-trifluoromethylphenyl trinor PGF2? is an analog of PGF2? that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2? isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2?. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,11?,15S-trihydroxy-17-trifluoromethyl-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic acid, isopropyl ester
  • Correlated keywords
    • prostaglandins F2? PGF2? FP receptors travoprosts latanoprosts glaucoma luteolysis reproductive biology PGs IOP intraocular pressure
  • Product Overview:
    Prostaglandin F2? (PGF2?), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity.{187,421,1651} 17-trifluoromethylphenyl trinor PGF2? is an analog of PGF2? that shares the meta-trifluoromethyl group of travoprost with the 17-phenyl trinor modification of latanoprost. It is anticipated to be a potent and selective agonist of the FP receptor, with potential applications in glaucoma and luteolysis. 17-trifluoromethylphenyl trinor PGF2? isopropyl ester is a lipophilic analog of 17-trifluoromethylphenyl trinor PGF2?. Isopropyl esters of PGs can serve as prodrugs, as they can be efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

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