17-<wbr/>phenyl trinor Prostaglandin F<sub>2?</sub>-<wbr/>d<sub>4</sub>

17-phenyl trinor Prostaglandin F2?–d4

CAT N°: 316810
Price:

From 108.00 91.80

17-phenyl trinor Prostaglandin F2?-d4 (17-phenyl trinor PGF2?-d4) contains four deuterium atoms at the 3, 3′, 4, and 4′ positions. It is intended for use as an internal standard for the quantification of 17-phenyl trinor PGF2? by GC- or LC-mass spectrometry. 17-phenyl trinor PGF2? is a metabolically stable analog of PGF2? and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2?.{2058} At the rat recombinant FP receptor expressed in CHO cells 17-phenyl trinor PGF2? inhibits PGF2? binding with a Ki of 1.1 nM.{1374} The isopropyl ester of 17-phenyl trinor PGF2?-d4 is slightly better than PGF2? isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.{1107}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,11?,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
  • Correlated keywords
    • GC/MS deuterium isotopes 17-phenyl-trinor-PGF2.alpha.-3,3,4,4-d4 17-pheny-trinor-PGF2alpha-3,3,4,4-d4 GC-MS LS/MS LC-MS mass spectrometry spectroscopy chromatography deuterateds
  • Product Overview:
    17-phenyl trinor Prostaglandin F2?-d4 (17-phenyl trinor PGF2?-d4) contains four deuterium atoms at the 3, 3′, 4, and 4′ positions. It is intended for use as an internal standard for the quantification of 17-phenyl trinor PGF2? by GC- or LC-mass spectrometry. 17-phenyl trinor PGF2? is a metabolically stable analog of PGF2? and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2?.{2058} At the rat recombinant FP receptor expressed in CHO cells 17-phenyl trinor PGF2? inhibits PGF2? binding with a Ki of 1.1 nM.{1374} The isopropyl ester of 17-phenyl trinor PGF2?-d4 is slightly better than PGF2? isopropyl ester in reducing the intraocular pressure in the cat eye without any irritation.{1107}

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