17-<wbr/>phenyl trinor Prostaglandin F<sub>2?</sub> cyclopropyl methyl amide

17-phenyl trinor Prostaglandin F2? cyclopropyl methyl amide

CAT N°: 10010810
Price:

From 109.00 92.65

Prostaglandin F2? (PGF2?) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2? binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2?.{2058} It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2? ethyl amide.{12894} 17-phenyl trinor PGF2? ethyl amide is used to reduce intraocular pressure related to glaucoma.{12188} 17-phenyl trinor PGF2? cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2?. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,11?,15S-trihydroxy-17-phenyl-18,19,20-trinor-prosta-5Z,13E-dien-1-cyclopropyl methyl amide
  • Correlated keywords
    • prostaglandins F2? PGF2? FP receptors luteolysis analogs bimatoprosts glaucoma intraocular pressure IOP PGs
  • Product Overview:
    Prostaglandin F2? (PGF2?) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2? binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2?.{2058} It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2? ethyl amide.{12894} 17-phenyl trinor PGF2? ethyl amide is used to reduce intraocular pressure related to glaucoma.{12188} 17-phenyl trinor PGF2? cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2?. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

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