16,16-<wbr/>dimethyl Prostaglandin A<sub>1</sub>

16,16-dimethyl Prostaglandin A1

CAT N°: 10080
Price:

From 131.00 111.35

16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. The ID50 for HSV-1 strains in Vero cells and human foreskin fibroblasts are 3.8-5.6 µg/ml and 4.6-7.3 µg/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 µg/ml.{811}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9-oxo-15R-hydroxy-16,16-dimethyl-prosta-10,13E-dien-1-oic acid
  • Correlated keywords
    • 16,16-dimethyl-pga1 prostaglandins metabolism-resistant analogs inhibits inhibition inhibitors viral replication HSV HIV-1 herpes simplex virus human immunodeficiency type 1
  • Product Overview:
    16,16-dimethyl PGA1 is a metabolism resistant analog of PGA1. In vitro, it inhibits the viral replication in both HSV and HIV-1 infection systems at concentrations that do not adversely alter cellular DNA synthesis. The ID50 for HSV-1 strains in Vero cells and human foreskin fibroblasts are 3.8-5.6 µg/ml and 4.6-7.3 µg/ml, respectively. The ID50 for T cells acutely infected with HIV-1 is 2.5 µg/ml.{811}

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