16-<wbr/>phenoxy tetranor Prostaglandin F<sub>2?</sub> methyl amide

16-phenoxy tetranor Prostaglandin F2? methyl amide

CAT N°: 10010562
Price:

From 82.00 69.70

Prostaglandin F2? (PGF2?) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2? are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor PGF2? is a metabolically stable form of PGF2? containing a 16-phenoxy group at the ?-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2?.{2058} 16-phenoxy tetranor PGF2? methyl amide is a lipophilic analog of 16-phenoxy tetranor PGF2?. Methyl amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

We also advise you