15(S)-<wbr/>HpETE

15(S)-HpETE

CAT N°: 44720
Price:

From 55.00 46.75

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 15S-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
  • Correlated keywords
    • 15-LOs 15-HpETEs 15S-HpETEs hydroperoxides 15(S)-HpETEs 15(S)HPETEs 15-lipoxygenases monohydroperoxy fatty arachidonic acids polyunsaturated 15s-hpete
  • Product Overview:
    15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4{391} or reduced to 15(S)-HETE by peroxidases.{3959,391} 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.{4194} 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO.{3959,454,588}

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