15(R),19(R)-<wbr/>hydroxy Prostaglandin F<sub>2?</sub>

15(R),19(R)-hydroxy Prostaglandin F2?

CAT N°: 16920
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From 59.00 50.15

19(R)-Hydroxylated prostaglandins (PGs) occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).{7578} 19(R)-Hydroxylated PGs are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.{2390} The 15(R)-hydroxy epimer of these 19-hydroxylated PGs is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated PGs is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.{1441}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9?,11?,15R,19R-tetrahydroxy-prosta-5Z,13E-dien-1-oic acid
  • Correlated keywords
    • prostaglandins hydroxylated 15R,19R-hydroxy-PGF2alpha 15R,19R-OH-PGF2alpha 15(R),19(R)-OH-pgf2alpha 15(R),19(R)-hydroxy-pgf2alpha 15R,19R-hydroxy-PGF2.alpha. 15R,19R-OH-PGF2.alpha. 15(R),19(R)-OH-pgf2.alpha. 15(R),19(R)-hydroxy-pgf2.alpha.
  • Product Overview:
    19(R)-Hydroxylated prostaglandins (PGs) occur in µg/ml concentrations in the semen of certain mammalian species, especially primates. In the case of humans, the compounds are primarily of the PGE series, and the hydroxyl stereochemistry is 15(S),19(R).{7578} 19(R)-Hydroxylated PGs are also found in the seminal plasma of marsupials, where F-type compounds of the 1 and 2-series predominate.{2390} The 15(R)-hydroxy epimer of these 19-hydroxylated PGs is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated PGs is not well established. In the F-series, 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.{1441}

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