1,4-PBIT (dihydro<wbr/>bromide)

1,4-PBIT (dihydrobromide)

CAT N°: 81510
Price:

From 25.00 21.25

1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS.{1292} Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • S,S’-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide
  • Correlated keywords
    • nitric oxide synthase inhibitors NOS
  • Product Overview:
    1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS.{1292} Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

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