1,2-<wbr/>Diheptanoyl-<wbr/><em>sn</em>-glycero-<wbr/>3-PC

1,2-Diheptanoyl-sn-glycero-3-PC

CAT N°: 25586
Price:

From 132.00 112.20

1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM.{41970,41971} Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6; Item No. 25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica.{41971} DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.{41972}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (7R)-4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxoheptyl)oxy]-3,5,9-trioxa-4-phosphahexadecan-1-aminium, inner salt, 4-oxide
  • Correlated keywords
    • Diheptanoylphosphatidylcholine Diheptanoyllecithin DHPCC7 Lecithin glycero3PC sn1 sn2 PC-12 SHSY5Y
  • Product Overview:
    1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM.{41970,41971} Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6; Item No. 25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica.{41971} DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.{41972}

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