1-Palmitoyl Lyso<wbr/>phosphatidic Acid

1-Palmitoyl Lysophosphatidic Acid

CAT N°: 10010094
Price:

From 59.00 50.15

1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Additionally, 1-palmitoyl LPA enhances the action of ?-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.{15000}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • hexadecanoic acid, 2-hydroxy-3-(phosphonooxy)propyl ester
  • Correlated keywords
    • GPCR G-proteins cells proliferation smooth muscles contractions platelets aggregation
  • Product Overview:
    1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.{13001,2656} Additionally, 1-palmitoyl LPA enhances the action of ?-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.{15000}

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