1-Oleoyl-2-<wbr/>hydroxy-<em>sn</em>-<wbr/>glycero-3-PE

1-Oleoyl-2-hydroxy-sn–glycero-3-PE

CAT N°: 25596
Price:

From 74.00 62.90

1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-?, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 ?g per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 1-oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine
  • Correlated keywords
    • PC-12 LPA-1 AM-095 IL2 CD-1d 2-H4 2-H-4 2H-4 IFN? Th-2
  • Product Overview:
    1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.{36851,36852,36853} It induces transient increases in intracellular calcium in PC12 rat neuronal cells in a concentration-dependent manner, an effect that can be blocked by the lysophosphatidic acid receptor 1 (LPA1) antagonist AM095 (Item No. 22141).{36852} 1-Oleoyl-2-hydroxy-sn-glycero-3-PE (100 ng/ml) increases IL-2 production in CD1d-stimulated murine natural killer T (NKT) cell hybridoma 2H4 cells.{36853} It also induces production of IL-4, but not IFN-?, in murine splenocytes when used at a concentration of 100 ng/ml and in mouse serum when administered at a dose of 1 ?g per animal, indicating induction of the T helper 2 (Th2) response. 1-Oleoyl-2-hydroxy-sn-glycero-3-PE levels increase in interscapular brown adipose tissue (iBAT) in mice following three-day cold exposure.{36851}

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