γ-Linolenic Acid

γ-Linolenic Acid

CAT N°: 90220
Price:

From 37.00 31.45

γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 6Z,9Z,12Z-octadecatrienoic acid
  • Correlated keywords
    • fatty acids PUFAs gamma-linolenic g-linolenic .omega.-6 omega-6 .gamma.-linolenic polyunsaturated w-6
  • Product Overview:
    γ-Linolenic acid (GLA) is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}

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