24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.{43943} It activates liver X receptors (LXRs)...
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€166.00 €141.10
(±)9,10-EpOME-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of 9,10-EpOME by GC- or LC-mass spectrometry (MS). (±)9(10)-EpOME (Item No. 52400) is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst.{651} It has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome.{407} Mitochondrial dysfunction is the main feature of (±)9(10)-EpOME cytotoxicity, which may be due to the diol metabolites as well as the parent epoxide.{1300,5617}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 100 µg, 25 µg, 250 µg, 50 µg |
|---|---|
| Shipping | dry ice |
| Molecular formula | C18H28D4O3 |
| Smiles | CCCCC/C([2H])=C([2H])C[C@](O1)([2H])[C@]1([2H])CCCCCCCC(O)=O, CCCCC/C([2H])=C([2H])C[C@](O1)([2H])[C@]1([2H])CCCCCCCC(O)=O, CCCCC/C([2H])=C([2H])C[C@](O1)([2H])[C@]1([2H])CCCCCCCC(O)=O, CCCCC/C([2H])=C([2H])C[C@](O1)([2H])[C@]1([2H])CCCCCCCC(O)=O |
| Molecular weight | 300,5 |
| Custom code | 3822.19 |
| Formulation | A solution in methyl acetate |
| Purity | ≥99% deuterated forms (d1-d4) |
| UNSPSC code | 12352100 |
Cayman Chemical’s mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.
Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.
Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.
Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.
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