(±)5(6)-DiHETE lactone

(±)5(6)-DiHETE lactone

CAT N°: 18343
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From 157.00 133.45

Eicosapentaenoic acid (EPA; Item No. 90110) is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases. (±)5(6)-DiHETE (Item No. 10467) is a possible metabolite produced from EPA following epoxidation of the ?-5 double bond. (±)5(6)-DiHETE lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHETE. While its biological activity is unknown, the selective capacity of (±)5(6)-DiHETE to form this lactone can be utilized to specifically quantify (±)5(6)-DiHETE in biological samples.{29654}

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