(±)5(6)-<wbr/>DiHET lactone

(±)5(6)-DiHET lactone

CAT N°: 51212
Price:

139.00 118.15

5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-?-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS.{39654} 5,6-DiHET potently induces vasodilation of isolated canine coronary arterioles, with 41 and 100% inhibition occurring at 0.01 and 100 pM, respectively.{12606} It also induces vasodilation in isolated human microvessels and increases intracellular calcium levels in a dose-dependent manner, an effect that can be blocked by the nitric oxide scavenger L-NAME (Item No. 80210).{43011}

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