(±)-<em>trans</em>-<wbr/>GK563

(±)-trans–GK563

CAT N°: 25732
Price:

140.00 119.00

trans-(±)-GK563 is a potent ?-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2; IC50 = 1 nM).{35898} It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 ?M). trans-(±)-GK563 (1 and 10 ?M) inhibits apoptosis induced by IL-1? and IFN-? in INS-1 ?-cells.

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