(±)-?-<wbr/>Tocopherol

(±)-?-Tocopherol

CAT N°: 27193
Price:

From 54.00 45.90

(±)-?-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.{15114,15117,8680} It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays.{15114,15117} It also reduces the synthesis of prostaglandin E2 (PGE2; Item No. 14010) induced by LPS in RAW 264.7 macrophages and by IL-1? in A549 cells (IC50s = 7.5 and 4 ?M, respectively).{8680} (±)-?-Tocopherol (10 ?M) inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1?. Serum levels of (±)-?-tocopherol are decreased in patients with cardiovascular disease.{15114} [Matreya, LLC. Catalog No. 1073]

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
  • Correlated keywords
    • 119-11-9 7540-59-2 54-28-4 E 308 E308 DL Tokoferol E2 PGE PGE2 RAW 264.7 IL1? A 549 i NOS COX2 73980-80-0 anti-oxidant antiinflammatory
  • Product Overview:
    (±)-?-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.{15114,15117,8680} It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays.{15114,15117} It also reduces the synthesis of prostaglandin E2 (PGE2; Item No. 14010) induced by LPS in RAW 264.7 macrophages and by IL-1? in A549 cells (IC50s = 7.5 and 4 ?M, respectively).{8680} (±)-?-Tocopherol (10 ?M) inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1?. Serum levels of (±)-?-tocopherol are decreased in patients with cardiovascular disease.{15114} [Matreya, LLC. Catalog No. 1073]

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