(±)-Nornico<wbr/>tine

(±)-Nornicotine

CAT N°: 20505
Price:

From 55.00 46.75

(±)-Nornicotine is an active metabolite of nicotine (Item No. 16535) and a nicotinic acetylcholine receptor (nAChR) agonist.{34465} It induces currents in Xenopus oocytes expressing human ?7 nAChRs or ?6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (±)-Nornicotine promotes cell migration and destabilizes cell-cell junctions in EA.hy926 endothelial cells.{34463} It is self-administered in rats.{34462,34464}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-(2-pyrrolidinyl)-pyridine
  • Correlated keywords
    • 13450-58-3 demethylnicotine demethyl EA.hy 926
  • Product Overview:
    (±)-Nornicotine is an active metabolite of nicotine (Item No. 16535) and a nicotinic acetylcholine receptor (nAChR) agonist.{34465} It induces currents in Xenopus oocytes expressing human ?7 nAChRs or ?6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (±)-Nornicotine promotes cell migration and destabilizes cell-cell junctions in EA.hy926 endothelial cells.{34463} It is self-administered in rats.{34462,34464}

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