(±)-10-<wbr/>hydroxy-12(Z),<wbr/>15(Z)-Octa<wbr/>decadienoic Acid

(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid

CAT N°: 37280
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From 89.00 75.65

(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid is an oxylipin. It is produced from ?-linolenic acid (Item Nos. 90210 | 21910) by the gut bacteria L. plantarum.{67084} (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic acid prevents increases in mRNA expression of the gene encoding SREBP-1c by the liver X receptor (LXR) agonist T0901317 (Item No. 71810) in HepG2 cells. It reduces LPS-induced increases in nitric oxide (NO) production in RAW 264.7 macrophages when used at a concentration of 10 µM.{69079}

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