β-Boswellic Acid

β-Boswellic Acid

CAT N°: 11693
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From 66.00 56.10

β-Boswellic acid is a pentacyclic triterpene originally isolated from Boswellia that has diverse bioactivities.{30044} It inhibits 5-lipoxygenase (5-LO) with an IC50 value of approximately 5 µM but is less potent than its derivative 3-acetyl-11-keto-β-boswellic acid (Item No. 11672).{6066} It inhibits cell proliferation in HL-60 cells with IC50 values of 3.7, 7.1, and 6.3 µM for DNA, RNA, and protein synthesis, respectively.{38153} In human umbilical vein endothelial cells (HUVECs) transiently deprived of oxygen and glucose, β-boswellic acid increases nitric oxide and increases phosphorylation of enzyme nitric oxide synthase (eNOS).{38155} It also increases calcium mobilization in platelets at concentrations ≥3 µM and induces platelet aggregation (EC50 = 8 µM).{38154}

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α-Boswellic Acid

α-Boswellic Acid

α-Boswellic acid is a pentacyclic triterpene and an isomer of β-boswellic acid (Item No. 11693) originally isolated from B. serrata.{46214,46215}...

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